The Exchange Stabilization Fund: How It Works

How it acts, how it works

Interferon beta (IFNβ) and glatiramer acetate (GA) were the first immunomodulators approved to the treatment of relapsing-remitting multiple sclerosis (MS) and clinically isolated syndromes. Despite the enlargement of the therapeutic armamentarium, IFNβ and GA remain the most widely drugs and the therapeutic mainstay of MS. Objective: To review the mechanisms of action of IFNβ and GA and main c...

How It Works and Why It Matters

This paper provides simulation practitioners and consumers with a grounding in how discrete-event simulation software works. Topics include discrete-event systems; entities, resources, control elements and operations; simulation runs; entity states; entity lists; and entity-list management. The implementation of these generic ideas in AutoMod, SLX, and Extend is described. The paper concludes w...

Process evaluation: how it works.

Process evaluation helps us to understand the planning process. This predominantly qualitative approach explains how and why decisions are made and activities undertaken. The focus includes feelings and perceptions of program staff. The evaluator's ability to interpret and longitudinally summarize the experience of program staff and community members is critical. Techniques discussed include pa...

Market integration: how it works

The Ketogenic Diet 2011: How It Works

Although the ketogenic diet (KD) has been widely accepted as a legitimate and successful therapy for epilepsy and other neurological disorders, its mechanism of action remains an enigma. The use of the KD causes major metabolic changes. The most significant of them seems to be the situation of chronic ketosis, but there are others as well, for instance, high level of polyunsaturated fatty acids...